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KMID : 0985520150200040209
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Korean Journal of Pancreas and Biliary Tract
2015 Volume.20 No. 4 p.209 ~ p.215
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Grave Clinical Course of Pancreatic Invasive Cancer Developed in the Patients with Branch Duct IPMN: A Report of Three Cases
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배대환:Bae Dae-Hwan
양지열:Yang Ji-Youl/김근모:Kim Keun-Mo/김형우:Kim Hyung-Woo/윤웅수:Yoon Woong-Su/조병하:Cho Byung-Ha/김진영:Kim Jin-Young/한정호:Han Joung-Ho/박선미:Park Seon-Mee
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Abstract
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Branch duct intraductal papillary mucinous neoplasms of the pancreas (BD-IPMN) without malignant features rarely developed into invasive cancer. However, invasive cancer is aggressive once an invasive change occurs. We report three cases of invasive cancers which developed in patients with BD-IPMN and they showed grave clinical courses. All patients were diagnosed with BD-IPMN < 3 cm without malignant features on imaging. Invasive cancer was detected at 2.5 years, 3.0 years, and 4.0 years after BD-IPMN detection in each patient. The intervals of invasive cancer and the last follow-up were 9 months, 3 years, and 1.5 years in the three patients, respectively. All patients were diagnosed with locally advanced pancreas invasive cancers and were treated with palliative chemotherapy or conservative management. The patients died at 3 months, 9 months, and 10 months after the diagnosis of invasive cancers, respectively. We report three cases of invasive cancer developed in BD-IPMN patients and followed fatal courses.
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KEYWORD
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Follow-Up Studies, Branch Duct, Intraductal Papillary Mucinous Neoplasm, Pancreatic Cancer
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